Chorea in Pregnancy

Sydenham's Chorea

Sydenham’s chorea is a delayed complication of group Aßhaemolytic streptococcal infections and forms one of the majorcriteria of acute rheumatic fever.It is characterised bychorea, muscular weakness, and a number of neuropsychiatricsymptoms. It is considered to be an autoantibody mediated disorderwith the evidence suggesting that patients with Sydenham’schorea produce antibodies that cross reac...

Penicillin in Rheumatic Chorea

Huntington's chorea.

The pharmacological treatment of Huntington's chorea has been based on the use of neuroleptic drugs, on the hypothesis that there is a functional dopaminergic hyperactivity in this illness (Agid, 1975). More recently, after the observation of reduced cholinergic and GABAminergic activity at the striatal level in brains of choreic subjects (McGeer et al., 1973; Stahl and Swanson, 1974; Bird and ...

Mutation in Huntington's chorea.

Huntington's chorea is inherited as an autosomal dominant and in the majority of published pedigrees the disease appears regularly in every generation. If the information is available, the disease can sometimes be traced through many generations over a considerable span of time. Investigation of the original family group described by Huntington has made it possible to trace their origin to the ...

Sydenham's chorea.

Sydenham's chorea (SC) is a disorder of the central nervous system (CNS) characterized by sudden, involuntary, arrhythmic, clonic, and purposeless movements. SC appears to provide a model for understanding various neuropsychiatric dysfunctions. Its relationship with attentional deficits, obsessive-compulsive symptoms (OCS) as well as movement disorders provides support for the hypothesis of the...